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Chloroquine Online



How and where to order Chloroquine Phosphate (Aralen) 250 mg, 500 mg tablets or capsules online on YMCA Liberia website:

Shop:CHEAP MEDS FOR SALE
Stores:PHARMA DOCTOR
Prices:from $0.73 per pill
Discount:5% coupon: 5OFF
Forms:250 mg, 500 mg capsules or tablets
Quantity:20-360 pills
Type:Chloroquine brand, Aralen generic
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Delivery:Regular airmail and express courier
Shipping:Worldwide, including USA, UK, Europe, Canada, Australia


Chloroquine (trade names include Aralen, Cloroquina, Novo-Chloroquine, Avloclor, Delagil, Lariago, Malarex, Resochin, Nivaquine) is an antimalarial medication from aminoquinolines pharmacological group. This medicine is used to treat and prevent malaria infections from Plasmodium vivax, Plasmodium ovale, Plasmodium malariae strains. It is also indicated for the treatment of amebiasis, amoebic liver abscess, some autoimmune disorders, rheumatoid arthritis, lupus erythematosus, sarcoidosis, in veterinary medicine. Aralen works by damaging DNA of malaria and amoebae. Chloroquine is in clinical, research, biomedicinal science trials as an investigational antiretroviral in humans with HIV-1/AIDS, COVID-19, SARS-CoV, as a potential antiviral agent against chikungunya fever, in anticancer therapy because of radiosensitizing and chemosensitizing properties, to inhibit lysosomal degradation of protein products.


Aralen (Chloroquine Phosphate) tablets


Related medications:

  • Albendazole (Albenza)
  • Amodiaquine (Camoquin)
  • Doxycycline (Vibramycin)
  • Hydroxychloroquine (Plaquenil)
  • Ivermectin (Stromectol)
  • Mebendazole (Vermox)
  • Mefloquine (Lariam)
  • Permethrin (Acticin)
  • Primaquine (Malirid)


    Pharmacological and medical categories:

  • Amebicides
  • Antiamoebics
  • Antimalarial medications
  • Antimalarial quinolines
  • Disease-modifying anti-rheumatic drugs (DMARDs)
  • Eye anti-infectives and antiseptics
  • Veterinary, pet meds


    ATC codes:

  • P - Antiparasitic products, insecticides and repellents
  • P01 - Antiprotozoals
  • P01B - Antimalarials
  • P01BA - Aminoquinolines
  • P01BA01 - Chloroquine


    ICD-10 codes:

  • Amoebiasis - A06
  • Other mosquito-borne viral fevers - A92
  • Chikungunya virus disease - A92.0
  • Human immunodeficiency virus [HIV] disease - B20
  • Plasmodium falciparum malaria - B50
  • Plasmodium vivax malaria - B51
  • Plasmodium malariae malaria - B52
  • Other parasitologically confirmed malaria - B53
  • Unspecified malaria - B54
  • Neoplasms - C00-D49
  • Sarcoidosis - D86
  • Disorders of glycoprotein metabolism - E77
  • Lupus erythematosus - L93
  • Other rheumatoid arthritis - M06


    Indications and usage:

    Aralen (Chloroquine Phosphate) is indicated for the:

  • Treatment of uncomplicated malaria due to susceptible strains of P. falciparum, P.malariae, P. ovale, and P.vivax.
  • Prophylaxis of malaria in geographic areas where resistance to chloroquine is not present.
  • Treatment of extraintestinal amebiasis.

    Aralen does not prevent relapses in patients with vivax or ovale malaria because it is not effective against exoerythrocytic forms of the parasites.

    Limitations of use in malaria:

  • Do not use chloroquine tablets for the treatment of complicated malaria (high-grade parasitemia and/or complications e.g., cerebral malaria or acute renal failure).
  • Do not use Aralen for malaria prophylaxis in areas where chloroquine resistance occurs, resistance to chloroquine is widespread in P. falciparum, and is reported in P.vivax.
  • Concomitant therapy with an 8-aminoquinoline drug is necessary for treatment of the hypnozoite liver stage forms of P.vivax and P.ovale.


    Dosage and administration:

    The dosage of chloroquine phosphate is often expressed in terms of equivalent chloroquine base. Each 500 mg tablet of Aralen contains the equivalent of 300 mg chloroquine base. In infants and children the dosage is preferably calculated by body weight.


    Dosage forms and strengths:

    Aralen (Chloroquine Phosphate) tablets for oral use: 250 mg and 500 mg.


    Overdosage:

    Signs and symptoms:

    Chloroquine is very rapidly and completely absorbed after ingestion. Toxic doses of chloroquine can be fatal. As little as 1 g may be fatal in children. Toxic symptoms can occur within minutes. The symptoms of overdosage may include nausea, vomiting, headache, drowsiness, visual disturbances, cardiovascular collapse, convulsions, hypokalemia, rhythm and conduction disorders including QT prolongation, torsades de pointes, ventricular tachycardia and ventricular fibrillation, followed by sudden potentially fatal respiratory and cardiac arrest. Immediate medical attention is required, as these effects may appear shortly after the overdose. Cases of extrapyramidal disorders have also been reported in the context of chloroquine overdose.

    Treatment

    Treatment is symptomatic and must be prompt with immediate evacuation of the stomach by emesis or gastric lavage followed by treatment with activated charcoal. Chloroquine (Aralen) overdose is a life-threatening emergency and should be managed with cardio-respiratory and hemodynamic support, monitoring of potassium along with management of arrhythmias and convulsions, as necessary. A patient who survives the acute phase and is asymptomatic should be closely observed until all clinical features of toxicity resolve.


    Contraindications:

  • Use of Aralen (Chloroquine Phosphate) tablets for indications other than acute malaria is contraindicated in the presence of retinal or visual field changes of any etiology.
  • Use of this medication is contraindicated in patients with known hypersensitivity to 4-aminoquinoline compounds.


    Warnings and precautions:

  • chloroquine-resistant malaria
  • treatment of exo-erythocytic forms of malaria
  • cardiac effects
  • hypoglycemia
  • retinopathy
  • central nervous system effects
  • muscular weakness
  • pediatric accidental ingestion
  • worsening of psoriasis and porphyria
  • hematological effects
  • auditory effects


    Side effects, adverse reactions:

    The most common adverse reactions have been identified during post-approval use of chloroquine or other 4-aminoqunoline compounds: maculopathy and macular degeneration, urticaria, nerve type deafness; tinnitus, sensorimotor disorders, hepatitis, increased liver enzymes, anorexia, nausea, vomiting, diarrhea, abdominal cramps, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, pancytopenia, aplastic anemia, reversible agranulocytosis, thrombocytopenia, neutropenia, convulsions, mild and transient headache, polyneuropathy, psychosis, delirium, anxiety, agitation, insomnia, confusion, hallucinations, personality changes, depression, hypotension, electrocardiographic changes.

    Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

    To report suspected adverse reactions of chloroquine phosphate pills, contact Sanofi-Aventis pharmaceutical company or your local FDA.


    Drug interactions:

  • Antacids and kaolin: antacids and kaolin can reduce absorption of chloroquine; an interval of at least 4 hours between intake of these agents and chloroquine should be observed.
  • Cimetidine: cimetidine can inhibit the metabolism of chloroquine, increasing its plasma level. Concomitant use of cimetidine should be avoided.
  • Insulin and other antidiabetic drugs: as chloroquine may enhance the effects of a hypoglycemic treatment, a decrease in doses of insulin or other antidiabetic drugs may be required.
  • Arrhythmogenic drugs: there may be an increased risk of inducing ventricular arrhythmias if Chloroquine (Aralen) is used concomitantly with other arrhythmogenic drugs, such as amiodarone or moxifloxacin.
  • Ampicillin: in a study of healthy volunteers, chloroquine significantly reduced the bioavailability of ampicillin. An interval of at least two hours between intake of ampicillin and chloroquine should be observed.
  • Cyclosporine: after introduction of chloroquine phosphate oral form, a sudden increase in serum cyclosporine level has been reported. Therefore, close monitoring of serum cyclosporine level is recommended and, if necessary, chloroquine should be discontinued.
  • Mefloquine: co-administration of chloroquine and mefloquine may increase the risk of convulsions. The blood concentrations of chloroquine and desethylchloroquine (the major metabolite of chloroquine, which also has antimalarial properties) were negatively associated with log antibody titers. Chloroquine taken in the dose recommended for malaria prophylaxis can reduce the antibody response to primary immunization with intradermal human diploid-cell rabies vaccine.
  • Praziquantel: in a single-dose interaction study, Aralen has been reported to reduce the bioavailability of praziquantel.
  • Tamoxifen: Concomitant use of chloroquine with drugs known to induce retinal toxicity such as tamoxifen is not recommended.


    Use in specific populations:

    Pregnancy

    Usage of chloroquine during pregnancy should be avoided except in the prophylaxis or treatment of malaria when the benefit outweighs the potential risk to the fetus. Radioactively tagged chloroquine administered intravenously to pregnant pigmented CBA mice passed rapidly across the placenta and accumulated selectively in the melanin structures of the fetal eyes. It was retained in the ocular tissues for five months after the drug had been eliminated from the rest of the body. There are no adequate and well-controlled studies evaluating the safety and efficacy of chloroquine in pregnant women.

    Nursing mothers

    Because of the potential for serious adverse reactions in nursing infants from chloroquine, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the potential clinical benefit of the drug to the mother.

    The excretion of chloroquine and the major metabolite, desethylchloroquine, in breast milk was investigated in eleven lactating mothers following a single oral dose of chloroquine (600 mg base). The maximum daily dose of the drug that the infant can receive from breastfeeding was about 0.7% of the maternal start dose of the drug in malaria chemotherapy. Separate chemoprophylaxis for the infant is required.

    Geriatric use

    Clinical studies of Aralen did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. However, this drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection and it may be useful to monitor renal function.


    How to store:

  • Keep Aralen (Chloroquine Phosphate) tablets out of the sight and reach of children. This medicine could harm them.
  • Do not store your medicine above 30°C.
  • Protect the pills from light and moisture.
  • Keep chloroquine tablets in the container they came in.
  • Do not take Aralen after the expiry date stated on the carton. The expiry date refers to the last day of that month.

    Medications should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines that are no longer required. This will help to protect the environment.


    Pregnancy categories:

  • Not Classified - Australia
  • Not Classified - United States


    Salts and other forms:

  • Chloroquine Base
  • Chloroquine Diphosphate
  • Chloroquine Hydrochloride
  • Chloroquine Phosphate
  • Chloroquine Phosphate Dibasic
  • Chloroquine Sulphate


    Synonyms, international and chemical names:

  • 7-Chloro-4-((4-(diethylamino)-1-methylbutyl)amino)quinoline
  • Chloraquine
  • Chlorochin
  • Chlorochina
  • Chlorochine
  • Chlorochinum
  • Chloroquin
  • Chloroquina
  • Chloroquini Phosphas
  • Chloroquini Sulfas
  • Chloroquinium
  • Chloroquinphosphat
  • Chloroquinsulfat
  • Chloroquinum
  • Chlorquin
  • Clorochina
  • Clorocwin
  • Cloroquina
  • Hlorokvin
  • Klorokiini
  • Klorokin
  • Klorokviin
  • Klowokin
  • Quinoline, 7-chloro-4-(4-diethylamino-1-methyl-butylamino)-


    Brands, generics, trade names:

  • Aralen - Sanofi-Aventis
  • Avloclor - AstraZeneca, Teva
  • Chloromax - Oboi Laboratories, Phil Pharmawealth
  • Chloroquine - Sanofi-Aventis, Teva, Watson Pharmaceuticals
  • Clo-Kit - Indoco Remedies
  • Cloroquina - Chile Laboratorios
  • Delagil - ICN Pharmaceuticals
  • Emquin - Merck
  • Klorokin - Zerboni Laboratorios
  • Lariago - Ipca Laboratories
  • Lariago-DS - Ipca Laboratories
  • Malarex - Alpharma
  • Malaquin - P.C. India Pharma
  • Nivaquine - Sanofi-Aventis, Beacon Pharmaceuticals
  • Nivaquine-P - Sanofi-Aventis, Nicholas Piramal
  • Novo-Chloroquine - Novopharm
  • Plasmoquine - Medchem Pharmaceuticals
  • Resochin - Bayer
  • Resochina - Bayer
  • Teva-Chloroquine - Teva


    APIs used in medicine in combinations with chloroquine:

  • Acetaminophen (Paracetamol)
  • Aminobenzoic Acid
  • Benzyl Alcohol
  • Bulaquine
  • Ephedrine Hydrochloride
  • Fluprednidene Acetate
  • Neomycin Sulfate
  • Prednisolone
  • Primaquine Phosphate
  • Proguanil Hydrochloride
  • Pyrimethamine
  • Quinacrine Hydrochloride
  • Theophylline
  • Vitamin B1 (Thiamine Hydrochloride)
  • Vitamin B5 (Calcium Pantothenate)
  • Vitamin B6 (Pyridoxine Hydrochloride)
  • Vitamin C (Ascorbic Acid)


    Here is a list of popular medications containing chloroquine as a main active pharmaceutical ingredient; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:

    Trade name of the drug Pharmaceutical forms and doses Companies
    Aralen
  • Tablets; Oral; Chloroquine Phosphate 150 mg
  • Tablets; Oral; Chloroquine Phosphate 250 mg
  • Tablets; Oral; Chloroquine Phosphate 300 mg
  • Tablets; Oral; Chloroquine Phosphate 500 mg
  • Sanofi-Aventis
  • C.T.S. Chemical Industries
  • Lariago
  • Injectable; Injection; Chloroquine Phosphate 40 mg / ml
  • Suspension; Oral; Chloroquine Phosphate 50 mg / 5 ml
  • Syrup; Oral; Chloroquine 80 mg / 5 ml
  • Tablets, Film-Coated; Oral; Chloroquine Phosphate 250 mg
  • Ipca Laboratories
  • Intima
  • Malarex
  • Syrup; Oral; Chloroquine Phosphate 120 mg / 5 ml
  • Tablets, Film-Coated; Oral; Chloroquine Phosphate 250 mg
  • Alpharma
  • Actavis
  • Dumex
  • KWH Marketing
  • Resochin
  • Injectable; Injection; Chloroquine Phosphate 40 mg / ml
  • Suspension; Oral; Chloroquine Phosphate 50 mg / 5 ml
  • Syrup; Oral; Chloroquine Phosphate 50 mg / 5 ml
  • Syrup; Oral; Chloroquine Phosphate 100 mg / 5 ml
  • Tablets, Dispersible; Oral; Chloroquine Phosphate 500 mg
  • Tablets, Film-Coated; Oral; Chloroquine Phosphate 250 mg
  • Bayer
  • Kern Pharma



  • References:

  • Chloroquine main article on Wikipedia: https://en.wikipedia.org/wiki/Chloroquine
  • Chloroquine compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Chloroquine
  • Chloroquine Phosphate compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Chloroquine-phosphate
  • Chloroquine medicine on DrugBank: https://go.drugbank.com/drugs/DB00608
  • Chloroquine Phosphate on DrugBank: https://go.drugbank.com/salts/DBSALT000025
  • Chloroquine FAQ on MedlinePlus (revised 10/15/2020): https://medlineplus.gov/druginfo/meds/a682318.html
  • Chloroquine Phosphate film-coated tablets drug label on DailyMed (revised April 15, 2020): https://dailymed.nlm.nih.gov/dailymed/drugInfo...
  • Chloroquine containing drugs on Drugs-About.com: https://drugs-about.com/ing/chloroquine.html
  • Chloroquine for sale on Pharma Doctor: https://pharma-doctor.com/chloroquine.html
  • Chloroquine international drug names on Drugs.com: https://www.drugs.com/international/chloroquine.html
  • Aralen (Chloroquine Phosphate, USP) tablets official prescribing information from the U.S. FDA (revised March 2017): https://www.accessdata.fda.gov/drugsatfda_docs/label/...
  • Aralen (Chloroquine Phosphate) tablets medication guide from MedicineNet (revised 03/23/2020): https://www.medicinenet.com/chloroquine-oral/article.htm
  • Avloclor (Chloroquine Phosphate) 250 mg tablets patient information leaflet from Medicines.org.uk (revised September 2016): https://www.medicines.org.uk/emc/files/pil.5490.pdf

    Revised: June 2021

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